(00:00) Loyal CEO Celine Halioua joins Jason (1:43) The human dream of achieving life extension (4:37) Celine’s background (8:48) Fount - Get $500 off at https://fount.bio/twist (10:19) Why Celine decided to start with a focus on dogs (16:43) Wegovy, Ozempic, and the category of drugs that Loyal is developing (20:44) Breaking down how the drugs work and the consequences of selective breeding (24:21) LinkedIn Jobs - Post your first job for free at https://linkedin.com/unicorn (25:36) Stem cell therapy and the placebo effect (33:29) Environmental factors to consider in drug development (37:05) The path to commercialization (39:27) Catalog - Get $1200 off right now at https://trycatalog.com/twist (40:56) Staying intellectually curious and the path to commercialization continued (46:11) Hitting Series A milestones with less than $500K of the original $5M raised in seed round (49:34) Lessons learned as a solo founder Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Check out Loyal: https://loyalfordogs.com/ FOLLOW Celine: https://twitter.com/celinehalioua FOLLOW Jason: https://linktr.ee/calacanis Thanks to our partners: (8:48) Fount - Get $500 off at https://fount.bio/twist (24:21) LinkedIn Jobs - Post your first job for free at https://linkedin.com/unicorn (39:27) Catalog - Get $1200 off right now at https://trycatalog.com/twist Listen here: Apple: https://podcasts.apple.com/us/podcast/this-week-in-startups-audio/id315114957 Spotify: https://open.spotify.com/show/6ULQ0ewYf5zmsDgBchlkr9 Overcast: https://overcast.fm/itunes315114957/this-week-in-startups-audio More from us: Twitter: https://twitter.com/twistartups Instagram: https://www.instagram.com/thisweekinstartups Official site: https://thisweekinstartups.com/ Subscribe to our YouTube to watch all full episodes: https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A Subscribe to TWiST Clips for all the best moments: https://www.youtube.com/channel/UCS7tJlcUA6PzVHEMo-X7ddg #startups #entrepreneurship #investing #angelinvesting #tech #news #business