A new Review proposes Saturated Fat is harmless and unfairly demonized. Does this reflect the scientific evidence? A look at the science of saturated fat, safe ranges and controversies. Saturated fat: villain and bogeyman in cardiovascular disease? Saturated fat is an emotional topic. Saturated fat raises cardiovascular disease if it's too high. Saturated fat isn’t bad. Health-promoting foods have Saturated fat. Replacing Saturated fat replaced with refined carbs doesn't help. Whole grains lower risk. Unsaturated fats also. PUFA, the lowest. Source of saturated fat matters. fish has saturated fat but also PUFAs. Dark chocolate is high in Saturated fat but its stearic acid which. we see benefit of saturated fat moderation in RCTs, usually PUFA is best. MUFA or carb, less consistent. UK Biobank: no evidence that saturated fat intake was associated with CVD, cardiovascular disease. Replacing saturated fat with MUFA or protein was associated with lower risk of death and CVD. Replacing saturated fat with starch or sugar (refined carbs) was associated with lower total death. PUFAs can come in fatty fish, nuts, seeds, vegetable oil, or in junk foods that contain PUFA oils. Saturated fat was associated with lower ischemic heart disease. saturated fat replaced with PUFA benefits CVD. PUFA consumption in place of saturated fat would reduce CHD. Linoleic acid replacing saturated fat associated with lower CHD and. Replacing saturated fat with polyunsaturated fat prevents CHD Connect with me: Facebook: https://www.facebook.com/DrGilCarvalho/ Twitter: https://twitter.com/NutritionMadeS3 Animations: Even Topland @toplandmedia References: 1-https://academic.oup.com/eurjpc/advance-article-abstract/doi/10.1093/eurjpc/zwac194/6691821 2- 2015 edition: https://pubmed.ncbi.nlm.nih.gov/26068959/ 2020 edition: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD011737.pub3/full 3-https://www.sciencedirect.com/science/article/pii/S0735109715046914 4-https://www.ahajournals.org/doi/full/10.1161/CIR.0000000000000510 5-https://academic.oup.com/ajcn/article/91/3/535/4597110%20 6-https://www.acpjournals.org/doi/abs/10.7326/m13-1788 7-www.lipidjournal.com/article/S1933-2874(09)00332-8/abstract https://www.lipidjournal.com/article/S1933-2874(21)00248-8/fulltext 8-https://www.mdpi.com/2227-9032/5/2/29/htm 9-https://www.ahajournals.org/doi/full/10.1161/JAHA.120.019814 10-https://www.lipidjournal.com/article/S1933-2874(21)00248-8/fulltext 11-https://www.sciencedirect.com/science/article/abs/pii/S0140673617322523 12-https://www.bmj.com/content/368/bmj.m688 13-https://www.mdpi.com/2072-6643/14/17/3603/htm 14-https://academic.oup.com/ajcn/article/103/2/356/4564754 15-https://www.nejm.org/doi/full/10.1056/nejmoa1800389 16-https://pubmed.ncbi.nlm.nih.gov/29511019/ 17-https://pubmed.ncbi.nlm.nih.gov/27543472/ 18-https://pubmed.ncbi.nlm.nih.gov/25161045/ 19-https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1000252 20-https://pubmed.ncbi.nlm.nih.gov/28125802/ 21-https://pubmed.ncbi.nlm.nih.gov/26746178/ 22-https://www.bmj.com/content/346/bmj.e8707 23-https://www.bmj.com/content/353/bmj.i1246 24-https://pubmed.ncbi.nlm.nih.gov/28526025/ 25-https://www.bmj.com/content/351/bmj.h3978.long 26-https://foodandnutritionresearch.net/index.php/fnr/article/view/680 27-https://www.nmcd-journal.com/article/S0939-4753(17)30237-5/fulltext 28-https://pubmed.ncbi.nlm.nih.gov/32307197/ 29-https://www.clinicalnutritionjournal.com/article/S0261-5614(20)30355-1/fulltext 30-https://www.jacc.org/doi/abs/10.1016/j.jacc.2020.05.077 31-https://www.lipidjournal.com/article/S1933-2874(21)00248-8/fulltext 32-https://link.springer.com/article/10.1007/BF02535856 33-https://food-guide.canada.ca/en/guidelines/ Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!. #NutritionMadeSimple #GilCarvalho 0:00 New Review 0:47 Dose 2:49 Replacement 6:42 Source 8:10 Standing questions 9:25 Rationale 10:00 Epidemiology 21:36 RCTs 23:05 Meta-analyses etc 28:08 The final analysis 32:35 Conclusion of the Review 34:03 Skepticism 34:54 Anatomy of Confusion 36:40 Scientific communication 38:24 The cycle of social media 40:21 Evolution 41:34 Saturated Fat: harmful or neutral? 42:10 Take-home message