Osteomyelitis | Causes & Symptoms | Bone Infection🩺 Like this video? Sign up now on our website at https://www.DrNajeebLectures.com/ to access 800+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $99 ONLY! Sign up now on our website at https://members.drnajeeblectures.com/#!/register-fast --------------------------------------------------------------------------------------------------------------------------- Why sign up for premium membership? Here's why! Membership Features for premium website members. 1. More than 800+ Medical Lectures. 2. Basic Medical Sciences & Clinical Medicine. 3. Mobile-friendly interface with android and iOS apps. 4. English subtitles and new videos every week. 5. Download option for offline video playback. 6. Fanatic customer support and that's 24/7. 7. Fast video playback option to learn faster. 8. Trusted by over 2M+ students in 190 countries. --------------------------------------------------------------------------------------------------------------------------- ▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬ 00:00:00 Introduction 00:01:10 Pyogenic and non-pyogenic Osteomyelitis 00:04:24 Potts disease 00:05:20 Route of entry 00:05:55 Haematogenous spread 00:12:32 Direct extension from neighboring soft tissues 00:17:24 Direct inoculation or implantation on microbes 00:19:10 Recap --------------------------------------------------------------------------------------------------------------------------- Defining Osteomyelitis (OM); Pyogenic & non-pyogenic infections. STAPH. AUREUS; most common organism in pyogenic OM & importance of this fact in directing empirical antibiotic therapy. Mycobacterium Tuberculosis; most common organism in non-pyogenic OM. POTT'S DISEASE; OM involving vertebrae; common in adults. Pathophysiology of OM; routes of entry of organism into Bone Marrow (BM): 1-Hematogenous spread/route. OM in children; long bone internal anatomy explained; significance of involvement of Metaphysis of long bones in OM of children. Pott’s Disease; vertebral involvement through hematogenous route; Bacteremia. Routes of entry continued; 2-Direct extension from neighboring Soft Tissue Infections; periosteal breach, example: DIABETIC FOOT ULCER. Mechanism of development of Diabetic Foot Ulcer: Atherosclerosis & Ischemia, Immunocompromised & Infection, Diabetic Neuropathy & inadvertent repetitive trauma. Ulcer deepens, leading ultimately to OM. 3-Microbes direct implantation into bone: Penetrating injury, surgery & Open Fractures. How bacteria destroy Periosteum? Damaging enzymes, inflammation, Oxygen Free Radicals. Periosteum; being relatively resistant to bacterial damage. --------------------------------------------------------------------------------------------------------------------------- Join this channel to get access to perks: Sign up now on our website at https://members.drnajeeblectures.com/#!/register-fast null Follow us on Facebook :- https://www.facebook.com/DrNajeeb/ Follow us on Instagram :- https://www.instagram.com/drnajeeblectures/