ACE inhibitors vs ARBs (mechanism of action) nursing review for NCLEX pharmacology. Angiotensin II receptor blockers (ARBs) and angiontensin-converting enzyme inhibitors (ACEI) both work to affect the renin-angiotensin-aldosterone system (RAAS). However, they affect this system in different ways but achieve the same results on the body. ACE Inhibitors inhibit ACE from converting Angiotensin I to Angiotensin II. While ARBs prevent angiotensin II from binding with angiotensin II type I receptor sites. Both of these mechanisms of action will prevent the role of angiotensin II in the body. These medications will cause vasodilation of vessels and decrease the release of aldosterone, which will cause the kidneys to excrete sodium and water and keep potassium. ACEI and ARBs are used to treat hypertension, heart failure, post MIs, and slow the progression of kidney disease in type 2 diabetics (diabetic nephropathy). ACE Inhibitors can lead to a dry, nagging cough along with angioedema, while this is rare to occur with ARBs. Nursing considerations for these medications are: educating the patient to avoid foods high in potassium, preventing rebound hypertension, lifestyle changes, monitoring for renal failure in patients who are dependent on the RAAS (severe heart failure) etc. Quizzes: ARBs:https://www.registerednursern.com/arbs-angiotensin-receptor-blockers-nclex-questions/ ACEI: https://www.registerednursern.com/ace-inhibitors-nclex-questions/ Notes: https://www.registerednursern.com/arbs-vs-ace-inhibitors-nursing-nclex-review/ More Pharmacology Reviews:    • Nursing Pharmacology   Nursing Gear: null Instagram: https://www.instagram.com/registerednursern_com/ Facebook: https://www.facebook.com/RegisteredNurseRNs Twitter: https://twitter.com/NursesRN #aceinhibitorsvsarbs #aceinhibitors #pharmacologynursing Website: https://www.registerednursern.com/ Popular Playlists: NCLEX Reviews:    • NCLEX Study Strategies   Fluid & Electrolytes:    • Fluid and Electrolytes Nursing   Nursing Skills:    • Nursing Skills Videos