We are in the midst of a revolution in the fields of genomics and public health. The availability of genome-wide sequence and variation data and the ability to rapidly generate new data have created unprecedented opportunities to study human biology, evolution, and disease. These tools are making it possible to carry out studies in the microbial pathogens that affect humans, such as Lassa, Ebola and Zika virus. They also may be used to develop and apply methods to investigate natural selection in the human genome and build new computational tools for studies of genomics and public health. This talk is part of the Survival symposium, a fascinating series of talks focusing on evolution and the challenges of building a better, safer and more survivable future. Watch the rest of Pardis Sabeti's talk here: https://www.youtube.com/watch?v=NBjPrf_PRO8 Watch more of the Survival symposium here: http://bit.ly/2iKfYRi