It's a good thing "Borderlands" has so many guns because you'll need to be extra-prepared for these tough boss fights. For this list, we’re looking at the most insane and psychotic bosses we’ve ever encountered across the “Borderlands” franchise. Our list includes the Empyrean Sentinel from "Borderlands: The Pre-Sequel" (2014), Billy the Anointed from "Borderlands 3" (2019), the Destroyer from "Borderlands" (2009), and more! Did any of these bosses give you a hard time? Share your frustration with us in the comments below. Watch more great boss fight videos here: The 10 BEST Bosses In Lego Games: https://www.youtube.com/watch?v=M_yoJepF-Yg The 10 HARDEST Elden Ring Bosses: https://www.youtube.com/watch?v=CvJqGcqamNo The 10 WORST Batman Arkham Boss Fights: https://www.youtube.com/watch?v=uQGoniRIGZ4 Big thanks to all the channels featured in our video! Shirrako: https://www.youtube.com/channel/UC7eAfUjR9gdIjoaoQaS0W-A Noctober: https://www.youtube.com/channel/UCUDTue0vG26TWpBcLhsjUDg Generic Gaming: https://www.youtube.com/channel/UCWSfEWhyuPPOAsFsVYIeYgQ Pallas7: https://www.youtube.com/channel/UC9MYgDcis-EGpPZyF6R-Vjw ViciousKiwi: https://www.youtube.com/channel/UCQIbAv4jCIr1mFrZwtM8fhg 100% Guides: https://www.youtube.com/channel/UCRvx1nQZ-YXvxc6IOB8mKPg JELLIS Gamer: https://www.youtube.com/channel/UC6Eq24RUh-ry84HDUBo7IoQ Bob Hall: https://www.youtube.com/channel/UCQgXmLWlIRVNvLvfVv9C-DQ reddi41: https://www.youtube.com/channel/UCef-dfsUC_XMAlJRbLSDGIg Subscribe for more great content! https://wmojo.com/mojoplays-subscribe Got ideas? Great, give them to us NOW! https://wmojo.com/suggest MojoPlays is your source for reviews, lists, Let's Plays, character origins and video game lore. #Borderlands #Gaming #VideoGames #FPS #Borderlands3 #Boss #Games #Gamer