An overview of ischemic stroke, including the etiologies, presentation, work-up, and management. Indications for tPA (i.e. alteplase) discussed. A few references for those who want to learn more... Complete 2019 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: https://www.ahajournals.org/doi/10.1161/STR.0000000000000211 Thombolytics in stroke - A discussion of the controversy from a neurologist: https://journals.sagepub.com/doi/abs/10.1177/1941874419838961 Thrombolytics in stroke - Another neurologist's opinion: https://journals.heart.org/bloggingstroke/2018/04/18/does-tpa-really-save-lives/ Thrombolytics in stroke - A skeptics review of the literature: https://first10em.com/thrombolytics-for-stoke/ Thrombolytics in stroke - Another skeptic: https://www.medscape.com/viewarticle/895159