#drnajeeb #medicines #pharmacology #medicaleducation #drnajeeblectures #hiv HIV AIDS | Sign Symptoms Transmission & Treatment | Dr Najeeb🩺 Like this video? Sign up now on our website at https://www.DrNajeebLectures.com/ to access 800+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $99 ONLY! Sign up now on our website at https://members.drnajeeblectures.com/ --------------------------------------------------------------------------------------------------------------------------- Why sign up for premium membership? Here's why! Membership Features for premium website members. 1. More than 800+ Medical Lectures. 2. Basic Medical Sciences & Clinical Medicine. 3. Mobile-friendly interface with android and iOS apps. 4. English subtitles and new videos every week. 5. Download option for offline video playback. 6. Fanatic customer support and that's 24/7. 7. Fast video playback option to learn faster. 8. Trusted by over 2M+ students in 190 countries. --------------------------------------------------------------------------------------------------------------------------- ▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬ 1. Introduction to HIV/AIDS. 2. Detailed explanation on Retrovirus. 3. Epidemiology of AIDS. 4. Structure of HIV virus. a) Structure of envelop. b) Different CD4+ cells. c) Interaction between GP120 and CD4+ cells. 5. Clinical aspects of GP120 and CCR5. 6. How HIV will produce AIDs and genetics of CCR5 in HIV resistance. 7. Genetic variations in GP120 due to which antidote for HIV has not developed yet. 8. Important features of GP120 molecule and its clinical aspects. 9. Attachment inhibitor and fusion inhibitor drugs. 10. ENV gene and envelop proteins. 11. Location and function of matrix proteins (p-17). 12. Location, composition of capsid and its clinical important (p-24). 13. RNA dimers and Positive polarity RNA v/s negative polarity RNA. 14. Important enzymes and their functions. (a) Reverse transcriptase. (b) Integrase. (c) Protease. 15. Some major differences between HIV1 and HIV2 . 16. Nucleocapsid proteins and their clinical importance. 17. Important genes and their functions. (1) GAG gene (2) POL gene (3) ENV gene 18. Introduction to Replication cycle and genomic variety. 19. Structure of virus. 20. HIV entry into CD4+ cells. 21. Replication inside cytoplasm (a) Dissolution of capsid. (b) Activity of Reverse transcriptase. (c) Integrase activity and formation of pro-viral DNA. (b)Clinical importance of integrase activity. 22. Drugs that inhibit enzymatic activity during replication. (a) Attachment inhibitor and fusion inhibitor drugs. (b) Nucleotide/nucleoside reverse transcriptase inhibitor. (c) Non-Nucleotide/nucleoside reverse transcriptase inhibitor. (d) Integrase inhibitor. 23. Structure of viral genome. (a) Long terminal repeats (promoter region & transcription factors). (b) Structural genes ( GAG, POL and ENV genes). (c) Concept of reading frames and formation of regulatory proteins from structural genes. 24. Defense system of HIV. 25. Budding of HIV. --------------------------------------------------------------------------------------------------------------------------- Join this channel to get access to the perks: Sign up now on our website at https://members.drnajeeblectures.com/ Follow us on Facebook:- https://www.facebook.com/DrNajeeb/ Follow us on Instagram:- https://www.instagram.com/drnajeeblectures/